Saravanan Muniyandy
Fatima College of Health Sciences, UAE
Title: Carboxymethyl sago cellulose: A novel carrier for dissolution enhancement
Biography
Biography: Saravanan Muniyandy
Abstract
Syntheses of biomass-based pharmaceutical excipients have received genuine attention due to their favorable environment profile. One of the major agricultural waste materials in Malaysia is lignocellulosic biomass from sago starch industries. Pharmaceutical grade carboxymethyl sago cellulose (CMSC) was successfully synthesized from Malaysian sago biomass. Hydrophilic nature of CMSC exploited in the dissolution enhancement of poorly water soluble drug. Drug-CMSC solid dispersions were produced and characterized by DSC, FT-IR and dissolution studies. CMSC solid dispersions have shown 2.6 times more dissolution than the native drug