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Previous Speakers

Abdoul Habib Beavogui

Abdoul Habib Beavogui

Maferinyah Training and Research Center in Rural Health of Maferinyah Guinea

Alexey Skripkin

Alexey Skripkin

BIOCAD Russia

Leandro Bueno Bergantin

Leandro Bueno Bergantin

UNIFESP-Escola Paulista de Medicina Brazil

Giovanni Pagano

Giovanni Pagano

Federico II Naples University Italy

Janos Szolcsanyi

Janos Szolcsanyi

Janos Szentagothai Research Centre Hungary

Bimal Roy Krishna

Bimal Roy Krishna

Touro University USA

Belamy B Cheung

Belamy B Cheung

Lowy Cancer Research Centre Australia

Michael O Baclig

Michael O Baclig

St Luke’s Medical Center Philippines

Middle East Pharma 2018

About Middle East Pharmacy and Pharmaceutical Congress

MIDDLE EAST PHARMA 2018

Middle East Pharmacy and Pharmaceutical Congress scheduled on September 17-18, 2018 Abu Dhabi , UAE. Conference includes Keynote presentations, Oral talks, Poster presentations, Symposia, Workshops, Exhibitions and Career development programs. The conference invites delegates from top Universities, Formulation Scientists, Researchers, Health care professionals, Pharmaceutical companies, students, business delegates and Young researchers, Health care professionals, Business delegates across the globe providing a better platform, interconnecting the latest research, technological developments as well as therapeutic aspects. Participating at Middle East Pharmacy and Pharmaceutical Congress will be good opportunity to meet eminent personalities in the fields of pharmaceutics and to learn the latest technological advancements.

Why to attend?

MIDDLE EAST PHARMA 2018 is a platform to discuss the innovative researches and developments in the Pharmaceutical Science. World eminent speakers, the most recent research advances, and the latest updates in Pharma industry are hallmarks of this conference.

Target Audience:

Our Organization would be privileged to welcome the:

  • Pharmaceutical Researchers

  • Pharmaceutical Industry Professionals

  • Academicians

  • Pharmaceutical Associations and Societies

  • Post-Doctoral

  • Young Researchers and Students

  • Pharmacists and Pharmacy Technicians from various areas

  • Clinical trial experts in Pharmaceutical and Life science

 

Scientific Sessions

TRACK 1:  Drug Discovery & Development

Drug discovery and development together are the complete process of identifying a new drug and bringing it to market. Discovery may involve screening of chemical libraries, identification of the active ingredient from a natural remedy or design resulting from an understanding of the target. Development includes studies on microorganisms and animals, clinical trials and ultimately regulatory approval. The process of drug discovery involves a combination of many disciplines and interests starting from a simple process of identifying an active compound. The discovery of a new chemical entity that modifies a cell or tissue function is but the first step in the drug development process. Once shown to be effective and selective, a compound which is to be discovered must be completely free of toxicity, should have good bioavailability and marketable before it can be considered to be a therapeutic entity.

 

TRACK 2: Novel Drug Delivery System

Drug delivery is the process of administering the drug or pharmaceutical product, in order to achieve desired therapeutic effect. The method by which drug delivered is important, as it has significant effect on its efficacy. Novel drug delivery system(NDDS) involves various approaches like medical devices or drug-device combination products. NDDS involves combining pharmaceutics polymer science, and molecular biology. Novel drug delivery systems are designed based on physical and biochemical mechanisms. Physical mechanism or controlled drug delivery system includes dissolution, osmosis, erosion and diffusion. Biochemical mechanism includes gene therapy, liposomes, nanoparticles, monoclonal antibodies. NDDS we can make ideal drugs, controlled delivery, selective targeting at site of action. Various drug delivery and drug targeted systems are developed, in order to minimize drug degradation, drug adverse effect, and in order to increase the drug bioavailability (amount of drug available at site targeted region). 

  • Hydrogel

  • Matrix Diffusion Types

  • Drug loaded erythrocytes

  • Osmotic Pressure Controlled

  • Chemically controlled

TRACK 3: Pharma and Technology

Nanotechnology is a study related to Nano sized particles, their function and practice with respect to different systems. The role of nanotechnology in the field of pharmaceutics has exceptionally altered the way of our understanding about drugs, Nano drugs or the use of nanoparticles as carrier of drug has become the basic fundamental or criteria for the production or design of a drug. Pharmaceutical nanotechnology is appliance of Nano science to pharmaceuticals as nanomaterials, and devices like diagnostic, drug delivery, biosensor, and imaging. Pharmaceutical nanotechnology has tuned diagnosis and focused treatment of disease at a molecular level. Nanotechnology is highly specialized field, which will revolutionize the pharmaceutical industry.

  • Nanomaterials

  • Drug carrier system

  • Molecular Diagnostics

  • Biosensor and biolabels

TRACK 4: Bioavailability & Bioequvialence

Bioavailability is defined as the rate and extent to which the active ingredient or active moiety is absorbed from a drug product and becomes available at the site of action.Bioequivalence is defined as the absence of a significant difference in the rate and extent to which the active ingredient or active moiety in pharmaceutical equivalents or pharmaceutical alternatives becomes available at the site of drug action when administered at the same molar dose under similar conditions in an appropriately designed study.

Bioavailability studies assess the relative fraction of the orally administered dose that is absorbed into the systemic circulation when compared to the bioavailability data for a solution, suspension, or intravenous dosage form and provide pharmacokinetic information related to distribution, elimination, effects of  nutrients on  absorption of  the drug, dose proportionality, linearity in pharmacokinetics of the active moieties and appropriate inactive moieties.

  • First Pass Metabolism

  • Relative Bioavailability

  • Absolute Bioavailability

  • Therapeutic relevance

  • Pka and Pkd Models

TRACK 5: Pharmacogenomics

Pharmacogenomics (constitute both branch i.e. pharmacology and genetic) is the study of the role of genetics in drug response. It deals with the effect of genetic variation on drug response in patient by correlating the gene expression with the pharmacokinetic parameter i.e. absorption, distribution metabolism and excretions. The Pharmacogenomics is used in the research to increase the safety and efficacy of the drug by targeting the drug at the particular site of genes. Pharmacogenetics also play important role in the study of effect of multiple genes in the pharmacological action of drugs.  Most of the drugs fail to show therapeutic effect at the latter stages it may be due to unexpected adverse effect of drug that may be due to the effect of various component of genes. Pharmacogenetics studies can be used at various stages of drug development. In clinical studies, pharmacogenetics can be used in stratification of patient based on their genotype, which correspond to their metabolizing capacity. This helps in prevention of various adverse drug reaction and better outcomes of clinical trial.

  • Toxicogenomics

  • Toxicogenomics

  • Pharmacoproteomics

  • Clinical Pharmacogenomics

  • Gene Polymorphism

TRACK 6: Pharmaceutical Formulations

Pharmaceutical formulation is a part of the drug development procedure. In this process Active ingredient is formulated into a final dosage form using proper excipients and technological procedures. A drug can have many forms depending upon how it is manufactured, route to be taken or the desired effects. The most common forms of drugs are tablets, capsules or solutions. Drug Formulation include Novel dosage forms, like tablets,sterile products, capsules, topical preparations, sustained-release and controlled release.

  • Topical and Transdermal Delivery

  • Ophthalmic Dosage Forms

  • Oral Solid Dosage Forms

  • Inhalation Dosage Forms

  • Parenteral Dosage Forms

TRACK 7: Clinical Research

Clinical trials are medical research studies involving people. They aim to test whether different treatments are safe and how well they work. Some trials involve healthy members of the public. Others involve patients who may be offered the option of taking part in a trial during their care and treatment. Clinical trials are carried out to try to answer specific questions about health and illness. Clinical trial is a systematic investigation in human subjects for evaluating the safety & efficacy of any new drug. Clinical trials are a set of tests in medical research and drug development that generate safety and efficacy data for health interventions in human beings.

  • Preclinical trails

  • Phases of clinical trails

  • Optimum dose finding

  • Single ascending dose limits

  • Multiple ascending dose limits

  • Post clinical trials

TRACK 8: Advances in Pharmaceutical Packaging

Packaging is the science, art and technology of enclosing or protecting products for distribution, sale and use. A final product is not accepted except it is properly Packaged and in some cases the major part of the formulation process may be concerned with selecting the correct package for the product. Packaging also refers to the process of Design, evaluation and fabrication of packages.

Advances in Packaging System: Blow-fill- seal technology is used to Produce aseptically sterile pharmaceuticals such as respiratory solutions, ophthalmics and wound care products.

Induction Cup sealing technology is used to create airtight and hermetic seals on the neck of the container based on the principle that a conductive material like aluminium foil heats up on exposure to high frequency magnetic field generated by an induction unit.

Tamper Evident Pharmaceutical Packaging have an indicator or barrier to entry which, if breached or missing, can reasonably be expected to provide visible or audible evidence to consumers that tampering has occurred. 

Novel Laser Coding Technology enables glass containers for parenteral use to be clearly coded at the glass syringe manufacturer and tracked from production to end customer.

  • Film wrappers

  • Blister package

  • Strip package

  • Bubble pack

  • Shrink seal and bands

TRACK 9: Pharmaceutical Analysis

The Pharmaceutical analysis is a branch of chemistry, which deals with determination of the quality and quantity of the pharmaceutical products. It is used for the separation of chemical components from the mixture and for the determination of the structure of the compounds. Analysis plays a vital role in the pharmacy. There are various methods for separation, identification and purification of chemical components by using Chromatography method, High performance liquid chromatography, Gas chromatography, Liquid chromatography, UV spectrometry, Mass Spectrometry.

  • Spectroscopic Techniques

  • Titration Methods

  • Quality Control

  • Chromatographic Techniques

  • UV Spectrometry

TRACK 10: Quality Assurance & Quality Control

Quality assurance is to prevent defects in deliverables in the planning process itself to avoid the rework, which cost a lot. Quality assurance is a proactive process, and it starts at the early stage of the project to understand the product stated and non-stated requirement and expectations, and then develop the plan to meet these requirements and expectations. Quality control is concerned with the operational activites and techniques that are used to fulfill the requirements of quality. The quality control process includes the activities focus on identifying defects in the actual product being produced. 

  • Good Manufacturing Practice

  • Analytical Techniques

  • Sample handlings

  • Calibration Procedures

  • Sampling and Analysis plan

TRACK 11: Pharmacokinetics & Pharmacodynamics

Pharmacokinetics is study of (ADME) Absorption, Distribution, Metabolism and Excretion of a drug, and pharmacodynamics is the study of relationship between the drug and its receptors, its mechanism of action and therapeutic effect. Both can play a role in drug–drug interactions. Many drugs share the same metabolic pathways or target the same receptors. This leads to the occurrence of pharmacokinetic and pharmacodynamic differences, respectively. Drug–drug interactions occur mainly during drug absorption, distribution (plasma drug binding protein), biotransformation and excretion.

  • Thereapeutic window

  • Area Under Curve

  • Biopharmaceuticals Process Validation

  • Drug Metabolism

  • Pka and Pkd Models

TRACK 12: Pharmacology & Toxicology

Pharmacology is the science of drugs, it deals with the interaction of externally administered chemical entity (drugs) with living systems. It encircles all aspects of knowledge about drugs, but most essentially those that are relevant to effective and safe use for medicinal purposes. Toxicology is the study of the poisonous effect of drugs and other chemicals (household, the environmental pollutant, industrial, agricultural, homicidal) with emphasis on detection, prevention, and treatment of poisonings. It also includes the study of adverse effects of drugs, since the same substance can be a drug or a poison, depending on the dose.

  • Neuro pharmacology

  • Pharmacognosy

  • Clinical toxicology

  • Receptors

  • Adverse Drug Reactions

TRACK 13: Drug Targeting and Drug Development

Target drug delivery system is a special form of drug delivery system where the pharmacologically active agent or medicament is selectively targeted or delivered only to its site of action or absorption and not to the non-target organs or tissues or cells. Targeted drug delivery implies for selective and effective localization of pharmacologically active moiety at pre identified (pre-selected) target in therapeutic concentration, while restricting its access to non-target normal cellular linings, thus minimizing toxic effects and maximizing therapeutic index. Targeting of drugs to special cells and tissues of the body without their becoming a part of systemic circulation is a very novel idea. A drug can be administered in a form such that it reaches the receptor sites in sufficient concentration without disturbing the extraneous tissue cells.

  • Passive Targeting

  • Inverse Targeting

  • Ligand Mediated Targeting

  • Liposomes

  • Nano Tubes

TRACK 14: Biopharmaceutics

Biopharmaceutics is the study of the physical and chemical properties of a drug and its dosage form in which the drug is given, and the route of administration on the rate and extent of systemic drug absorption. Biopharmaceutics is an integral component of the overall drug development cycle. The vitality of the drug substance and the medication regardless detailing ahead absorption, Furthermore in vivo conveyance of the drug of the site about action, will be portrayed as an arrangement for occasions that precede elicitation of a drug’s restorative impact.

  • Therapeutic drug monitoring (TDM)

  • Toxicokinetics 

  • Drug concentrations

  • Invivo-invitro protein binding

  • Drug metabolism

  • Protein half life

  • Physical Pharmacy: Physical–Chemical Principles

TRACK 15: Pharmacovigilance

Pharmacovigilance is “the science and activities relating to the assessment, understanding, detection, and prevention of adverse effects or any other drug-related problems”. Pharmacovigilance is the process and science of controlling the safety of medicines and taking action to decrease risks and increase benefits from medicines. It provides complete and clear information related to drug safety and various risks and benefits associated with them. Pharmacovigilance can help in providing information of unintended and severe adverse events which could not be provided by clinical trials involving in-vivo method. It increases the impact of pharmacovigilance on patient welfare and public health and to know what is pharmacovigilance.

  • Detection And Evaluation Of Drug Safety

  • Pharmacovigilance Legislation

  • Pharmacovigilance And Healthcare System

  • Methods Of Pharmacovigilance

TRACK 16: Regulatory Affairs

Regulatory Affairs a blend of science and administration to achieve an important objective within a drug development organization. Everything relating to drugs from the earliest non-clinical studies, through development, into routine manufacture and marketing. It can add compelling impact for patients and drug companies. The role of regulatory affairs is to establish and execute a regulatory strategy to ensure that the collective efforts of the drug development team results in a product that is approvable by global regulators but is also differentiated from the competition in some way and also is to ensure that the company’s activities, from non-clinical research through to advertising and promotion, are conducted in accordance with the regulations and guidelines established by regulatory authorities.

  • Good Manufacturing Practice

  • Regulatory Compliance

  • Drug Labelling Approvals

  • Drug Marketing Approvals

  • Manufacturing And Regulatory Compliance

TRACK 17: Pharmacy Practice

Pharmacy Practice acknowledge to the needs and wants of the people who use the pharmacists services to provide the best or most favourable, evidence-based care. The pharmacists concentrate on effective medicines management and aim to optimise the ease that patients acquire from their prescribed treatment as well as the supply of medicines.

The Pharmacy Practice is to provide medications and other health care products and services and to help people and society to make the best of them. The scope of pharmacy practice includes synthesizing and dispensing medications, modern services related to health care, which includes clinical services, considering medications for safety and efficacy, and furnishing drug information. Pharmacists practice includes community pharmacies, hospitals, clinics, skilled nursing facility, psychiatric hospitals, and regulatory agencies.

  • Pharmaceutical Care

  • Drug Information

  • Prescription and Incompatibilities

  • Future Pharmacy Practice

  • Patient Counselling

  • Pharmacy Practice Research

  • Transcribing  Dispensing Administration

  • Hospital Pharmacy

  • Community Pharmacy

 

 

Market Analysis Report

Pharmaceutical Market - Global

Pharmaceuticals are one of the world's most beneficial ventures.In 2008 alone, the pharmaceutical business sold $773 billion in items around the world a number that has reliably developed for as long as 8 years and is anticipated to increment again by 2.5 to 3.5 percent in 2017, as per the medication statistical surveying firm IMS Health.

In any case, the procedure that transforms look into dollars into pharmaceuticals is a moderate and regularly strenuous one. It now takes a normal of 12 to 15 years and up to $1.7 billion for a medication to go from revelation to advertise, as indicated by The Pharmaceutical Research and Manufacturers of America. Also, regardless of constantly and cash contributed, just a modest bunch of medications are affirmed by the FDA every year.

The laborious medication endorsement prepare uncovers a focal truth about Big Pharma: it's a standout amongst the most seriously controlled businesses on the planet. The U.S. Nourishment and Drug Administration (FDA) and its European Union partner, the European Medicines Agency (EMEA), represent each part of a medication's improvement from chemicals utilized as a part of the medication and clinical study directions, called conventions, to bundling segments and showcasing materials. This strict oversight is intended to ensure persistent wellbeing, and pharma organizations consider administrative oversight important. The consistent weight to hold fast to government commands shapes each part of a pharma company's association, operations, and culture. For instance, sedate organizations keep up capable administrative undertakings divisions-the offices that arrangement with government offices and they have a tendency to be hazard disinclined.

The Pharmaceutical industry's long successful strategy of placing big bets on a few molecules, promoting them heavily and turning them into blockbusters worked well for many years, but its R&D productivity has now plummeted and the environment’s changing. There are few trends which are reshaping the marketplace.

Pharmaceuticals represented a US$300 bn-a-year market globally as of 2015, the World Health Organization states. The global pharmaceutical market is expected to surpass US$400 bn by 2018. Worldwide prescription drug sales forecasted to grow at a robust 6.5% (CAGR) through 2022 to reach $1.06trn . 32% of the 2022 increase in sales to come from orphan drugs (+$95bn).

 

 

Pharmaceutical Market - Middle East

The pharmaceutical and healthcare sectors in the Middle East and North Africa (MENA) region will be shaped by numerous factors in 2017, including a slowdown in public sector growth as a result of low oil prices, regional challenges on the back of heightened pressure on drug prices and economic instability. We forecast MENA's pharmaceutical expenditure to increase to USD33.4bn in 2017, up from USD32.2bn in 2016. We also highlight two additional themes that will define the pharmaceutical and healthcare markets of MENA in 2017.

The pharmaceutical and healthcare sectors in the Middle East  region will be shaped by numerous factors in 2017, including a slowdown in public sector growth as a result of low oil prices, regional challenges on the back of heightened pressure on drug prices and economic instability. The forecast of pharmaceutical expenditure to increase to USD33.4bn in 2017, up from USD32.2bn in 2016.

Pharmaceutical Market - United Arab Emirates (UAE) 

The pharmaceutical market in the United Arab Emirates (UAE) is set to grow from just over $3 billion in 2015 to $5.7 billion by 2020, driven by increased healthcare expenditure, mandatory health insurance, and growing medical tourism.

According to research, UAE is quickly gaining popularity as a medical tourism destination due to its low costs, English-speaking medical staff, and virtually non-existent queues for treatment. Indeed, the Dubai Health Authority is working to develop the medical tourism sector, aiming to attract 1.3 million medical tourists annually by 2021. The revenue on medical tourism is expected to grow by 13% annually for the next five years.

    

 

Top universities in UAE:

  • Gulf Medical University
  • Dubai Pharmacy College
  • University of Sharjah 
  • Al Ain University of Science and Technology
  • Ras al-Khaimah Medical and Health Sciences University
  • Ajman University

 

 

 Related Conferences:

 

1. Annual Congress on Drug Formulation & Analytical Techniques September 03 - 04, 2018 Dubai, UAE

2. Annual Congress on Chemistry in Drug Discovery & Designing April 16-17, 2018 Dubai, UAE

3. World Congress on Bioavailability & Bioequivalence April 16-18, 2018 Dubai, UAE

4. World Congress on Bio-organic and Medicinal Chemistry July 19-21, 2018 Dubai, UAE

5. International Pharmacodynamics and Pharmacotherapeutics Conference October 18-19, 2018 Dubai, UAE

6. International Conference and Exhibition on Pharmacovigilance & Drug Safety June 21-22, 2018 London, UK

7. International Conference on Biopharma and Biotherapeutics October 24-25, 2018 Boston, Massachusetts, USA

8. World Congress on Pharmacology & Therapeutics September 17-18, 2018 | San Antonio, Texas, USA

9. International Conference and Expo on Drug Discovery, Designing & Development September 06-07, 2018 London, UK

10. International Conference on Pharmacy and Pharmaceutical Sciences February 15 - 16, 2018 London, United Kingdom

11. International Conference on Nanopharmaceutics and Advanced Drug Delivery August 16-17, 2018, Dublin, Ireland

12. Annual International Conference on Pharmaceutical Sciences 7th – 8th May 2018 Athens, Greece

13. International Conference and Exhibition on Pharmaceutical Sciences & Research Dubai, UAE, June 8-30, 2018

14. World Congress of Pharmacy and Pharmaceutical Sciences 2 - 6 September 2018, Glasgow, UK

15. International Conference On Pharmacology, June 18-20, 2018 Tokyo, Japan 

16. International Conference on Medicinal Chemistry, July 4-6, 2018, Strasbourg, France

17. World Congress on Pharmaceutical Sciences and Innovations in Pharma Industry February 26- 27, 2018 London, UK

18. International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 19-21, 2018 Berlin, Germany

19. International Conference and Exhibition on Pharmaceutical Development and Technology May 11-12, 2018 Tokyo, Japan

20. International Conference and Exhibition on Pharmacovigilance & Drug Safety June 21-22, 2018 London, UK

21. Annual European Pharma Congress May 07-09, 2018 Frankfurt, Germany

22. International Conference and Exhibition on Pharmaceutical Nanotechnology and Nanomedicine April 18-19, 2018 Las Vegas, Nevada, USA

23. International Conference on Analytical and Bio analytical Techniques October 31- November 01, 2018 Columbus, Ohio, USA

24. International Conference on Pharmaceutical Formulations & Drug Delivery September 17-18, 2018 | Philadelphia, Pennsylvania, USA

25. International Conference on Clinical Trials September 24-26, 2018 | Chicago, Illinois, USA

26. World Congress on Pharmaceutical Sciences September 28-29, 2018 | Montreal, Canada

27. Annual Medicinal & Pharmaceutical Sciences Congress July 05-06, 2018 Bangkok, Thailand

28. Global Pharmacovigilance & Clinical Trials Summit July 16-17, 2018 Sydney, Australia

29. World Congress on Advanced Pharmacy and Clinical Research July 16-17, 2018 Sydney, Australia

30. International Conference and Exhibition on Pharmacology and Ethnopharmacology July 18-19, 2018 Atlanta, Georgia, USA

Related Societies:

1. Drug Information AssociationPharmaceutical Association of Malaysia

2. Pharmaceutical Group of the European UnionRegulatory Affairs Professionals Society

3. Chinese American Biopharmaceutical Society

4. Parenteral Drug Association

5. International Society for Pharmaceutical Engineering

6. Association of Clinical Research Organizations

7. Pharmaceutical and Novel Drug Delivery Healthcare Sciences Society

8. International Academy of Compounding Pharmacists

9. European Pharmaceutical Union

10. American Society for Pharmacology and Experimental Therapeutics

11. Association of Clinical Research Organizations

12. American Association of Pharmaceutical Scientists (AAPS)

13. US Food and Drug Administration (FDA)

14. American Society for Clinical Laboratory Science (ASCLS)

15. National Cancer Institute Center for Cancer Research (NCI)

16. American Association for Clinical Chemistry (AACC)

17. American Society for Pharmacology and Experimental Therapeutics (ASPET)

18. Association of Clinical Research Organizations (ACRO)

19. International Pharmaceutical Manufacturers Group (IPMG) 

20. American Association of Colleges of Pharmacy (AACP),

21. American Pharmacists Association(APhA),

22. American Society for Pharmacy Law American Society of Consultant Pharmacists (ASCP), 

23. American Society of Health-System Pharmacists (ASHP),

24. Professional Compounding Centers of America.

25. European Association of Employed Community Pharmacists in Europe (EPhEU),

26. European Pharmaceutical Union (EPU)

27. Controlled Release Society (CRS)

28. Institute of Pharmacy Management International (IPMI)

29. International Academy of Compounding Pharmacists (IACP)

30. International Federation of Pharmaceutical Manufacturers Associations (IFPMA)

 

 

Past Conference Report

ME Conferences conducted the eleventh World Congress on Pharmaceutical Sciences and Innovations in Pharma Industry at Hotel Hyatt Place Amsterdam, Netherlands amid February 27-28, 2017.The conference was composed based on "Most recent Trends in Pharmacy: Spanning the Gap in Research and Product Commercialization". Besides, the systems administration sessions established the framework for quite a while commendable coordinated efforts between many start-up and enormous ventures.

Pharmaceutical Sciences 2017 saw an amalgamation of unbeatable speakers who illuminated the group with their insight and confabulated on different novel subjects identified with the field of Pharma Industry and Pharma Sciences. This congress not just presented the most recent improvements in the field yet additionally gave answers for the various difficulties experienced in building up a Pharma Industry.

Meeting Series might want to pass on a warm appreciation to all the Honorable visitors, Keynote Speakers, Delegates, Media Partners and Exhibitors for their investment in Pharmaceutical Sciences 2017.

The conference was initiated with the Honorable presence of the Keynote forum. The list includes:

Christopher Tirotta, Director Cardiac Anesthesia, USA.

Geoffroy Lumay, Associate professor - Soft Matter Physics chair, Belgium.                                  

Tirasak Pasharawipas, Professor in Medical Science Department, Thailand.                 

Pierre A. Morgon MRGN Advisors, Switzerland.                                                               

Harish Rajak, Assistant Professor of Pharmaceutical Medicinal Chemistry, India.                  

Pillhun SonProjects Coordination Manager at CAS a division of the American Chemical Society, USA.

 

New updates: Pharmaceutical Sciences

Researchers Interface Protein To Seizure Suppression

As indicated by new examination directed by scientists seizures can be supressed in the brain by a protein called T-cell intracellular antigen-1 (TIA-1).

This investigation gave another understanding on epilepsy– a neurological issue in which nerve movement in mind is influenced prompting repetitive, ridiculous seizures.A scientist says that TIA-1 helps in the control of quality articulation amid cell push. His exploration focusses on the concealment of serious electrical tempests of cerebrum which prompt seizures.

They believed that TIA-1 was incorporated into seizure concealment yet the examination discoveries prescribed something uniqueThe examination creators watched the elements of a catalyst in the mind called cyclooxygenase-2 (COX-2). This catalyst produces prostaglandins; synthetic exacerbates that help in the execution of general undertakings, alongside memory and learning.

 

The present investigation distinguished that seizure concealment was connected with a bring up in COX-2 articulation in neurons. The analysts meant to comprehend the connection between TIA-1 and COX-2. They began their work by arranging, directing and dissecting tests.

A Scientist presented the primary TIA-1's thorough articulation profile in the ordinary mind. Hefound that TIA-1 smothers epileptogenesis – a moderate procedure of ordinary cerebrum to end up epileptic. His exploration planned to comprehend the sub-atomic systems behind epilepsy; especially, the qualities required with seizure improvement and epileptogenesis.

 

New Findings Could Help Comprehend and Treat Glaucoma

Scientists have found two particular gatherings of short particles that control quality articulation in the eyes liquid of individuals with two unique types of glaucoma.
The differential articulation of these microRNAs is critical as it could enable specialists to discover more qualities that are connected to glaucoma, more data about how the diverse kinds of glaucoma harm the optic nerve and pointers of potential treatment intercessions.
For the investigation, Scientists inspected miRNA in the fluid amusingness of 12 patients with a typical condition called essential open point glaucoma and another 12 with the uncommon condition peeling glaucoma, which is more hard to treat. They at that point contrasted the miRNA profile of each and that of 11 people with sound eyes who filled in as controls.
As announced in Human Molecular Genetics, they found a huge distinction in the declaration of three miRNAs (miR-125b-5p, miR-302d-3p and miR-451a) between essential open edge glaucoma and the controls. 
 
They additionally found a critical contrast in the statement of five miRNAs (miR-122-5p, miR-3144-3p, miR-320a, miR-320e and miR-630) between peeling glaucoma and controls. 
 
Albeit the majority of these miRNAs have not beforehand been related with glaucoma, Liu and group do have some proof proposing that miR122-5p may target three qualities known to be related with glaucoma. An underlying take a gander at the pathways of alternate miRNAs demonstrated those are likely additionally required with glaucoma. 
 
Liu and group are currently exploring what these miRNAs do in the trabecular meshwork, which is in charge of ceaselessly depleting the liquid made in the ciliary body to feed and oxygenate a region of the eye that has no immediate blood supply.
 

The Future of Pharma-3D Printing

3D Printing (3DP) empowers the precise statement of medication and excipients, conceivably inflicting a change in angle in answer configuration, produce and make use of.Early-degree medicate development, (for instance, preclinical investigations and primary-in-human trials) could be speeded up with the aid of making use of three-D Printing to fast deliver definitions with terrific size adaptability requiring little to no effort, on request.3DP ought to bolster detailing development since it has the capability to create fast item cycles for checking out, for example, excipient similarity and medicine discharge.3DP ought to quicken the sphere of customized answer through moving remedy a long way from a 'one size suits all method' in the direction of personalisation.
 
3D printing (3DP) is estimate to be a completely modern innovation inside the pharmaceutical segment. in particular, the primary benefits of 3DP lie within the technology of little clusters of prescriptions, each with custom-made doses, shapes, sizes and discharge characteristics. The fabricate of prescriptions along those lines might also at lengthy last activate the concept of customized prescribed drugs turning into a truth. in the shorter time period, 3DP could be reached out for the duration of the medication advancement process, walking from preclinical development and scientific trials, via to cutting side medicinal care. on this audit, we provide an auspicious factor of view on the inspirations and ability makes use of of 3DP prescribed drugs, and additionally a reachable perspective on how 3DP could be coordinated over the pharmaceutical field.
 

Conveyance Benefit: How Implantable Drug Delivery Gadgets are Helping Persistent Care

Implantable drug eluting devices(also known as implantable drug delivery systems) offer a few preferences over ordinary oral or parenteral medication conveyance strategies. For example, they can give confined, site particular medication delivery, which is particularly imperative in applications, for example, cardiology and oncology, where focused conveyance can enhance the adequacy of treatment and limit reactions or harm to sound tissue.The measurement necessities regularly are lower than options, additionally lessening the potential for side effects.Also, sedate eluting gadgets can enhance understanding consistence, one of the best difficulties in human services, as around half of ordinary drugs are not utilized as prescribed.The treatment regimen can be less complex since it requires less specialist's visits and doses than customary therapies.

Uses of implantable drug eluting devices incorporate, among others, diabetes administration, contraception, HIV/AIDS avoidance, incessant agony administration, cardiology, oncology, and focal sensory system (CNS) wellbeing. Alongside subcutaneous implantation, different body locales can fill in as implantation destinations (e.g. intravaginal, intravascular, intraocular, intrathecal, and peritoneal).

There are two classes of drug-eluting devices: Biodegradable and non-biodegradable. Biodegradable drug-eluting devices (likewise alluded to as bioerodible) utilize biocompatible materials, for example, polyesteramide (PEA) and poly lactic-co-glycolic corrosive (PLGA) to convey drugs, and, once embedded, disintegrate after some time.

Rather than biodegradable, non-biodegradable drug delievery devices(additionally alluded to as biodurable) utilize biocompatible materials like silicone elastic (polydimethylsiloxane or PDMS), polyethylene-vinyl acetic acid derivation (EVA), and thermoplastic polyurethane (TPU) to convey drugs. Non-biodegradable medication eluting gadgets can be planned as grid, store, or osmotic frameworks to convey drugs by means of dispersion or osmosis and are by and large less exorbitant than biodegradable devices. Non-biodegradable medication eluting gadgets can be refilled with solution (e.g. by means of infusion) and the gadget's belongings are very quickly reversible upon expulsion

Non-biodegradable Pathway TPU excipients are intended to be adaptable and customisable to an expansive scope of compound and physical properties giving assortment along various measurements, including drug discharge energy (short or long haul); dynamic pharmaceutical fixing determination (hydrophobic or hydrophilic APIs); handling strategies (expulsion, infusion trim or dissolvable throwing), and mechanical performance. These traits furnish engineers with plan adaptability.

Digital PHARMA

As we know it where innovation is riding increasingly more human practices, it is essential that drug store is likewise within the combination. by 2020, experts expect that during excess of 20 billion everyday articles may have the capacity to catch, get, and proportion statistics via a worldwide system related collectively with the aid of most economical sensors, GPS, and the cloud. Ongoing biometric information will consequently be stuck via these articles and used to soak up extra about the effect of manner of lifestyles on perpetual diseases and wellness, and in the end exchange conduct to decorate our wellbeing including telemedicine counsels and flexible well being packages and trackers, enable customers to land up e-sufferers.
 
some part of that is wearables. changing way of lifestyles of youngsters’ requests community. The human services phase represents a noteworthy piece of the wearable innovation market it, thinking about the improvements in a few applications around there over the maximum recent  many years. cellular telephones with wearable sensors, embedded medicinal devices, and locally located telehealth devices can assist screen and deal with the strength of a patient.

 

Chemically Modified Drug to Treat HIV

In an enormous breakthrough that would accelerate a possible HIV treatment, a studies team has altered the chemical structure of a present antiviral drug to ease it in reaching cells and tissues where HIV resides.

The use of a physiochemical scheme that alters the properties of the drug dolutegravir, Scientists took the changed drug and positioned it into nanocrystals. The produced drug crystals effortlessly distributed in the course of the body to tissue reservoirs of HIV infection.

The advanced drug scheme prolonged the existence of the drug and its entry into "hidden body compartments," from the muscle site of injection at the same time as growing its action in lowering viral growth. The tissues covered the lymph nodes, the bone marrow, the intestine and the spleen.

The modified drug crystals have been not poisonous, did not destroy apart with temperature modifications and had been stable for months of time. All organs and physical functions remained intact after treatment.

Researcherssays covered with components of fats,thecrystals efficaciously maneuvered via cellular defensivemembranes and have been stored interior cells for weeks.

When stored interior cells known as macrophages, the drug was gradually discharged from the crystal in an altered inactive form known as a "prodrug". The cell after that breaks the prodrug into an active drug, and the active drug is then launched to circulate from the cell and tissue stores.

The power of this system is that it not simplest may be powerful in improving HIV care and prevention. However can be applied to many classes of drugs beyond HIV, including drugs used to deal with cancer, other infectious illnesses and degenerative diseases that have an effect on the brain

The new products can optimize HIV restrictive increase in order that techniques that can eliminate viral infection might achieve success

New Drug Capsule for HIV Treatment

Researchers have developed a pill which can deliver every week's worth of HIV pills in a single dose. This advance could make it a lot easier for patients to adhere to the strict schedule of dosing required for the drug cocktails used to fight the virus.

The novel drug is designed therefore the patients can acquire it easily once in a week then the drug will release steadily all through the week. This kind of delivery system couldn't only enhance patients' adherence to their remedy schedule however additionally be utilized by people prone to HIV exposure to help prevent them from turning into infected.

One of the primary limitations to treating and preventing HIV is adherence.
The capacity to make doses much less common stands to enhance adherence and make an extensive effect on the affected person level.

Scientists developed a new drug-delivery system can probably help patients with HIV/AIDS, in addition to many other diseases

Several clinical trials have evaluated whether antiretroviral pills can prevent HIV infection in healthy populations. Those trials have had blended success, and one main impediment to preventative treatment is the problem in getting people to take the essential pills each day

Researchers believed that a drug delivery pill they developed in may assist to cope with this problem. Their pill includes a star-shaped structure with six arms that can be loaded with tablets, folded inward, and encased in a smooth coating. After the pill is swallowed, the arms unfold and steadily release their cargo.

In their authentic model, the whole star shape was made from one polymer that both gives structural aid and carries the drug payload. This made it harder to design new pills that could release drugs at varying ratesbecause any changes to the polymer composition may disrupt the pill's structural integrity.
To overcome that, the researchers designed a novel form in which the backbone of the star structure remains a strong polymer, however every of the six arms might be full of a unique drug-loaded polymer. This makes it simpler to design a pill that releases drugs at unique rates.

Nanopharmaceutics

Nanotechnology is a study associated with nanoparticles, their ability and practice regarding unique frameworks. The part of nanotechnology within the discipline of pharmaceutics has outstandingly changed the approach for our comprehension approximately medicinal drugs, Nano pills or the usage of nanoparticles as transporter of medicine has become the critical component or criteria for the introduction or plan of a medication.

Many therapeutic agents offer a low beneficial dose (dose liable for efficacy)/useless dose (dose eliminated or responsible for toxicity) ratio, particularly because of the fact that therapeutic agents ought to ensure in one single item all of the functions required to deliver the remedy, which results in compromises in their physico-chemical layout.  Scientists have introduced the concept of priming the body to obtain the remedy with the aid of uncorrelating these capabilities into distinct items sequentially administered: a nanoprimer occupying transiently the primary pathway liable for therapeutic agent restricted benefit/threat ratio observed by way of the healing agent. The idea became evaluated for specific nature of healing dealers: For nanomedicines they designed a liposomal nanoprimer providing preferential hepatic accumulation without signal of acute toxicity. This nanoprimer changed into capable of increase the blood bioavailability of nanomedicine correlated with a decrease hepatic accumulation. Subsequently this nanoprimer markedly superior anti-tumor efficacy of irinotecan loaded liposomes inside the HT-29 tumor model while in comparison to the nanomedicine alone.

 

 

To Collaborate Scientific Professionals around the World

Conference Date September 17-18, 2018

Speaker Opportunity

Supported By

Research & Reviews in Pharmacy and Pharmaceutical Sciences International Journal of Drug Development and Research Journal of Pharmaceutics & Drug Delivery Research Journal of Nanomedicine & Nanotechnology

All accepted abstracts will be published in respective Conference Series LLC LTD International Journals.

Abstracts will be provided with Digital Object Identifier by


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Keytopics

  • Medicinal Plants
  • Pre-Clinical Drug Development
  • Accelerated Stability Studies
  • Adverse Drug Reaction (ADR)
  • Agonists And Antagonists
  • Allergen Immunotherapy
  • Antigen And Antibody Reaction
  • Biochemistry
  • Bioinformatics And Computational Biology
  • Biomolecular Chemistry
  • Cheminformatics
  • Clinical Trials
  • Combinatorial Chemistry
  • Community Pharmacy
  • Competitive Analysis Of Drug
  • Cytokines And Biological Modifiers
  • Desensitization
  • Drug Accessibility
  • Drug Administration
  • Drug Adsorption Mechanism
  • Drug Analysis
  • Drug Delivery Systems
  • Drug Dependence
  • Drug Distribution
  • Drug Metabolism
  • Drug Resistance
  • Drug Response
  • Drug Solubility
  • Drug Tolerance
  • Drug-Metabolism
  • Efficacy And Safety
  • Ethnomedicine
  • Excretion Of Drugs
  • Genetic Engineering
  • Health Care System
  • Hospital Pharmacy
  • Hypersensitivity
  • Immune Response
  • Immunisation
  • Immunogenicity
  • In Silico Methods
  • Inducers And Inhibitors
  • Lead Compound
  • Leveraging Technology
  • Medical Anthropology
  • Medication Therapy Management (MTM)
  • Metabolic Compound
  • Molecular Docking
  • Molecular Interaction
  • Molecular Pharmacy
  • Monoclonal Antibodies
  • Nanopharmacology
  • Novel Medicine
  • Patent And Approval
  • Pharmaceutical Formulation
  • Pharmaceutical Industry
  • Pharmacoepidemiology
  • Pharmacognosy
  • Pharmacology
  • Pharmacotherapy
  • Phytochemistry
  • Potency Of Drug
  • Quality Assurance
  • Quality Control
  • Radiopharmaceuticals
  • Tachyphylaxis
  • Target Molecule
  • Toxicology
  • Unapproved Drugs
  • Vaccination
  • Virtual Screening