7^th International Pharmacy and Pharmaceutical Conference November 28-29, 2024 Rome, Italy

Track 01:  Pharmaceutical Sciences

Drugstore's field of pharmaceutics deals with the process of turning untested or new chemicals into  specifics that cases may use safely and effectively. The wisdom of lozenge form design is another name for it. Multitudinous composites have pharmacological capabilities, but they frequently bear redundant backing to reach therapeutically applicable attention at their areas of action. The expression of a pure medicine material into a lozenge form is the responsibility of pharmaceutics. The discovery and development of new specifics and treatments depend on a wide range of scientific disciplines that are combined in the pharmaceutical lores. Following are the five primary orders into which pharmaceutical lores can be divided, with several subcategories within each.

Track 02: Bio Pharmaceuticals

Medicinals made with biotechnology are known as biopharmaceuticals. They're made via processes other than direct birth from a native natural source, and they include proteins and nucleic acids employed for remedial or in vivo individual purposes. Medicinals made from living effects make up the vast maturity of biopharmaceutical goods. The assiduity generally doesn't consider small patch specifics to be biopharmaceutical in nature. Still the conception is constantly expanded by members of the press, business community, and fiscal community to cover non-biotech specifics.

• complex medicines
• cells or organisms
• Proteins, including antibodies
• Peptides
• Organs and tissues
• Vaccines

Track 03: Radiopharmaceuticals

A radiopharmaceutical is a medication that has both medicinal and diagnostic uses. It is made up of an organic molecule and a radioisotope link. The radioisotope is delivered to particular organs, tissues, or cells through the organic molecule. The radioisotope is chosen based on these characteristics. For diagnostic (imaging), where the radiation must depart the body before being detected by a specialised instrument, radioisotopes that generate penetrating gamma rays are used. The radiation released by an imaging isotope often disappears entirely after one day due to radioactive decay and routine bodily waste.

• Cytokines, Interleukins
• Erythropoietin, Thrombopoietin
• Insulin, GH, Gonadotropins

Track 04: Advanced Pharmaceutical Technology

Pharmaceuticals technology focuses on transforming small molecules, proteins, and genes into therapeutic products. These include new drug therapies, drug design, molecular modeling, high throughput screen, production and stability considerations, and delivery systems of protein and gene therapeutics.

• Biotechnological Aspects Of Product Development: concepts and techniques.
• Development of recovery processes for recombinant proteins and peptides
• Resealed erythrocytes as drug carriers
• Supramolecular drug delivery

Track 05: Innovation in Drug Discovery Technology

Technology has played a significant role in the advancement of drug discovery. In order to obtain better data more quickly, automation, nano fluidics, imaging, software, and assay technologies have all been very important. Is drug discovery at a point where additional advancements are neither necessary nor practical? Although there are varying views on this and the most of the data is anecdotal, technological innovation is important for enhancing the drug discovery process and merits discussion. I go to four or five drug research conferences each year in the US and Europe. This presents an excellent chance for me to view exhibitions, listen to speeches, and read posters.

• De novo design
• Similarity searching
• Shape recognition
• Pharmacophore mapping
• Machine/deep learning

Track 06: Computational Chemistry in Drug Discovery and Design

One method is computational chemistry, which simulates chemical reactions and computes the chemical characteristics of atoms and molecules using physics-based algorithms and computers. To compute and forecast events in drug design and discovery, such as the drug binding to its target and the chemical attributes for the designing potential of new medications, a variety of computational chemistry methodologies are used.

Track 07: Advanced Pharmaceutics-Formulation Development

Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form.

• Discovery and Development
• Preclinical Research
• Clinical Research
• FDA Drug Review
• FDA Post-Market Drug Safety Monitoring

Track 08: Nanotechnology in Drug Delivery

The study, design, development, synthesis, manipulation, and use of substances, machines, and systems at the nano actions could be bypassed scale is known as nanotechnology. The field of medicine known as nano medicine makes use of biocompatible nanoparticles and nanorobots for a variety of applications in living organisms, including diagnostics, delivery, sensing, and actuation. Nanomedicine aims to prevent and treat a variety of disorders. Drugs with extremely low solubility have a variety of biopharmaceutical delivery problems, such as restricted bio accessibility following oral intake, reduced ability to diffuse into the outer membrane, need for greater intravenous dosage, and unfavourable side effects prior to conventionally formulated vaccination process. However, by utilising nanotechnology methods in the drug delivery mechanisms, all of these restrictions could be bypassed.

Track 09: Biomarkers in Drug Discovery

In addition to having a significant impact on medical practise, medication research and development now increasingly depend on disease biomarkers. Allowing earlier, more accurate drug safety and efficacy evaluations is the challenge for biomarkers. For the foreseeable future, they will continue to play a bigger role in medication development. Greater comprehension of the process of illness progression and therapeutic intervention is required before biomarkers may fulfil their proper function. In addition, a deeper comprehension of the prerequisites for clinical endpoint validation and application, biomarker selection and validation, and biomarker assay technique validation and application is required. While the therapeutic target is still being discovered and the concept is being developed, biomarkers must be taken into consideration.

• Molecular
• Histologic
• Radiographic
• Physiologic characteristics

Track 10: Pharmacogenomics

Pharmacogenomics examines how inherited and acquired genetic variation affects a patient's ability to respond to a medicine by tying gene expression or single-nucleotide polymorphisms to pharmacokinetics and pharmacodynamics. In order to achieve optimum effectiveness with a minimum of side effects, pharmacogenomics strives to create reasonable methods to optimise drug therapy with respect to the genotype of the patients. It is envisaged that by using pharmacogenomics, pharmaceutical pharmacological therapies can depart from the so-called "one-dose-fits-all" strategy. Pharmacogenomics aims to do away with the trial-and-error approach to prescription by enabling doctors to take into account the patient's genes, how these genes operate, and how this may affect the effectiveness of the patient's present or future treatments.

• Pharmacokinetics
• Pharmacodynamics
• New drug development
• Patient genetic testing
• Clinical patient management.

Track 11: Pharmaceutical Research and Development

Investment on pharmaceutical research and development Despite the fact that they are projected to increase at a compound annual growth rate (CAGR) of 2.8% through 2022, stakeholders and experts have noticed a decline in the return on investment (ROI). Pharmaceutical firms are coming under more and more pressure to either increase the success rates of their R&D or lower the cost of failure, which a breakthrough would ordinarily pay. From the first hazardous dose through market approval, the pharma research and development process has an average success rate of 4.9%. However, experts are debating whether the number of FDA-approved pharmaceuticals in 2016 was lower than in 2015, which raises the possibility that drug approvals have already peaked and will continue to drop. with a dismal forecast for increasing pharmaceutical research and development success rates.

• Basic research
• Applied research
• Experimental development

Track 12: Clinical Research & Clinical Trials

Clinical research is the study of health and illness in people. It is the way we learn how to prevent, diagnose and treat illness. Clinical research describes many different elements of scientific investigation. Simply put, it involves human participants and helps translate basic research into new treatments and information to benefit patients. Clinical trials as well as research in epidemiology, physiology and pathophysiology, health services, education, outcomes and mental health can all fall under the Clinical research umbrella. Clinical trial is a type of Clinical research study. A clinical trial is an experiment designed to answer specific questions about possible new treatments or new ways of using existing (known) treatments. Clinical trials are done to determine whether new drugs or treatments are safe and effective. Clinical trials are part of a long, careful process which may take many years to complete. First, doctors study a new treatment in the lab.

Track 13: Medical Devices Clinical Research

In the context of medical devices, a clinical trial or a clinical investigation can be defined as any systematic investigation or study on one or more human subjects undertaken to assess the safety or performance Different types of Clinical research are used depending on what the researchers are studying. Below are descriptions of some different kinds of clinical research. Treatment Research generally involves an intervention such as medication, psychotherapy, new devices, or new approaches to surgery or radiation therapy. Prevention Research looks for better ways to prevent disorders from developing or returning. Different kinds of prevention research may study medicines, vitamins, vaccines, minerals, or lifestyle changes. Diagnostic Research refers to the practice of looking for better ways to identify a particular disorder or condition. Screening Research aims to find the best ways to detect certain disorders or health conditions.

Track 14: Microbiology Clinical Research

Microbiology research is far less regular than understudy endeavors in the other significant regions of science. This is incompletely because of the simplicity, in view of size, with which the "large scale" territories have frameworks to work with; therefore extends are effectively conceptualized and performed utilizing natural abilities including the noticeable world. For the most part one timetables an assortment of customary classroom lab practices in the "full scale" disciplines which require no significant bits of gear nor extensive amounts of various materials; at that point understudies regularly utilize these labs to create thoughts for inquire about activities suited to their loving .

Track 15: Oncology Clinical Research

Phase I dose-finding trials, phase II studies to establish efficacy in a single tumour type, phase III trials contrasting current standards of care with potential improvements in care, and phase IV studies extending safety and activity data in a post-marketing scenario are now part of the science of clinical trials in oncology. As a result, we can anticipate greater cure rates for some metastatic tumours as well as locally contained cancers. For patients who received treatment outside of clinical trials and trial participants who had advanced stages of malignant diseases, researchers have significantly increased median overall survival statistics. Patients participating in clinical trials for advanced colorectal cancer are an illustration of this extension of median overall survival in the presence of advanced, incurable disease.

• Single-arm trials
• Placebo-controlled trials
• Crossover trials, factorial trials
• Noninferiority trials cancer

Track 16: Stem Cell and Genetic Clinical Research

A novel treatment area of contemporary medicine is gene therapy. Its development is a natural outcome of the revolution ushered in by the development of recombinant DNA technology in the 1970s. Although gene therapy is still very experimental, it has the potential to be a significant therapeutic approach. In theory, it permits the introduction of genetic material into the tissues and organs of patients. As a result, damaged genes can be removed or have their normal functions restored. Additionally, the process enables cells to acquire new capabilities, such as the ability to produce immune system mediator proteins that aid in the fight against cancer and other disorders. Monogenic hereditary illnesses like cystic fibrosis were formerly thought to be the main targets for gene therapy.

• Curing Diabetes
• Parkinson's disease
• Spinal cord injury
• Debilitating