Pharmacogenomics

Pharmacogenomics examines how inherited and acquired genetic variation affects a patient's ability to respond to a medicine by tying gene expression or single-nucleotide polymorphisms to pharmacokinetics and pharmacodynamics. In order to achieve optimum effectiveness with a minimum of side effects, pharmacogenomics strives to create reasonable methods to optimise drug therapy with respect to the genotype of the patients. It is envisaged that by using pharmacogenomics, pharmaceutical pharmacological therapies can depart from the so-called "one-dose-fits-all" strategy. Pharmacogenomics aims to do away with the trial-and-error approach to prescription by enabling doctors to take into account the patient's genes, how these genes operate, and how this may affect the effectiveness of the patient's present or future treatments.

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